Methyl iodide → HCID 178488380、化合物
反応式
[CH3:1][I:2].[CH3:3][O:4][C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:14]=1[NH:13][C:12](=[S:15])[NH:11][CH:10]2[CH3:16]>CC(C)=O>[IH:2].[CH3:3][O:4][C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:14]=1[N:13]=[C:12]([S:15][CH3:1])[NH:11][CH:10]2[CH3:16]参加物
4
実験手順
Methyl iodide (1.92 g, 14 mmol) was added to a solution of 8-methoxy-4-methyl-3,4-dihydro-1H-quinazoline-2-thione (940 mg, 5 mmol) in acetone (6 ml), and the mixture was stirred for 3 h at r.t. The precipitated title compound (1.2 g, 76%) was filtered off and was used without further purification in the next step.
後処理
- customThe precipitated title compound (1.2 g, 76%)
- filtrationwas filtered off
- customwas used without further purification in the next step
出典と根拠
- ORDレコード
- ord-91b7206c3ea343f3b2098f5d7b4e9c15
- 出典データセット
- uspto-grants-2010_09
- 特許番号
- US07790733B2
反応ノート
読み込み中…