Phenylthiourea → [5-(4-Methoxy-phenyl)-thiazol-2-yl]-phenyl-amine

HRID 1713649

反応式

HRID 1713649 の反応式
CO[C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10]2[S:11][C:12]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[CH:13][N:14]=2)=[CH:5][CH:4]=1.C1(NC(N)=S)C=CC=CC=1>C(Cl)Cl.CO>[CH3:22][O:21][C:18]1[CH:17]=[CH:16][C:15]([C:12]2[S:11][C:10]([NH:9][C:6]3[CH:5]=[CH:4][CH:3]=[CH:8][CH:7]=3)=[N:14][CH:13]=2)=[CH:20][CH:19]=1

参加物

4

反応物 2

HCID 676454PhenylthioureaHCID 11266955(4-Methoxy-phenyl)-[5-(4-methoxy-phenyl)thiazol-2-yl]-amine

生成物 1

HCID 58923516[5-(4-Methoxy-phenyl)-thiazol-2-yl]-phenyl-amine

試薬・触媒・溶媒 1

HCID 21226129Dichloromethane methanol溶媒

実験手順

The title compound is prepared as described in Example 4 for (4-methoxy-phenyl)-[5-(4-methoxy-phenyl)thiazol-2-yl]-amine but using phenylthiourea. Title compound: ES-MS: 283.0 [M+H]+; single peak at tR=7.89 min (System 1); Rf=0.50 (CH2Cl2/MeOH, 98/2).

後処理

  1. customThe title compound is prepared

出典と根拠

ORDレコード
ord-83b9af0788d0450f9264c901b3393e89
出典データセット
uspto-grants-2010_09
特許番号
US07795288B2

関連ノート

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