Formaldehyde → 2,3,4-Trihydroxy-5-(piperidin-1-ylmethyl)benzaldehyde

HRID 1714699

反応式

HRID 1714699 の反応式
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:7]=O.[OH:9][C:10]1[C:17]([OH:18])=[C:16]([OH:19])[CH:15]=[CH:14][C:11]=1[CH:12]=[O:13]>C(O)C>[OH:9][C:10]1[C:17]([OH:18])=[C:16]([OH:19])[C:15]([CH2:7][N:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)=[CH:14][C:11]=1[CH:12]=[O:13]

参加物

5

反応物 3

HCID 712FormaldehydeHCID 8082PiperidineHCID 750642,3,4-Trihydroxybenzaldehyde

生成物 1

HCID 592358682,3,4-Trihydroxy-5-(piperidin-1-ylmethyl)benzaldehyde

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

20.4 g (0.24 mol) of piperidine were added to 19.2 g (0.24 mol) of a 37% aqueous formaldehyde solution in 140 ml of ethanol. Then 25.0 g (0.16 mol) of 2,3,4-trihydroxybenzaldehyde were added thereto. The reaction mixture was refluxed for one hour, developing a dark brown color. After cooling, a beige-brown solid precipitated out, which was filtered out and dried.

後処理

  1. temperatureThe reaction mixture was refluxed for one hour
  2. temperatureAfter cooling
  3. customa beige-brown solid precipitated out
  4. filtrationwhich was filtered out
  5. customdried

出典と根拠

ORDレコード
ord-533e92d502dd4930888b752d63c59d71
出典データセット
uspto-grants-2010_09
特許番号
US07799096B2

関連ノート

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