化工社化工社 化学情報印刷レポート · 研究参考用
4-Aminobenzoic Acid → Carbamazepine 4-aminobenzoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Aminobenzoic Acid | HCID 978 | — |
| 反応物 | Carbamazepine | HCID 2554 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Carbamazepine 4-aminobenzoic acid | HCID 68425507 | — |
反応手順
40 mg (0.1693 mmol) of carbamazepine and 30 mg (0.1421 mmol) of 4-aminobenzoic acid were dissolved in approximately 3 mL methanol. Slow evaporation of the solvent yielded clear plates of carbamazepine:4-aminobenzoic acid (2:1) co-crystal. The co-crystal was analyzed via IR spectroscopy and single-crystal x-ray diffraction.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07803786B2 |
| 出典データセット | uspto-grants-2010_09 |
| ORD ID | ord-44bb3b9cb73747d187051a5a3f9e2af5 |
| 出典メモ | uspto-grants-2010_09 |