Hydroxyamine hydrochloride → HCID 178492604、化合物
反応式
C([O-])(=O)C.[Na+].[CH3:6][O:7][C:8]1[CH:17]=[CH:16][C:11]([O:12][CH2:13][C:14]#[N:15])=[CH:10][CH:9]=1.Cl.[NH2:19][OH:20]>CO>[OH:20][NH:19][C:14](=[NH:15])[CH2:13][O:12][C:11]1[CH:16]=[CH:17][C:8]([O:7][CH3:6])=[CH:9][CH:10]=1参加物
5
実験手順
Add sodium acetate (5.1 g, 62 mmol) to 4-methoxyphenoxyacetonitrile (5.0 g, 31 mmol) and hydroxylamine hydrochloride (4.3 g, 62 mmol) in methanol (100 mL). Stir the resulting mixture at room temperature for 20 hours. Filter the resulting mixture through Celite, concentrate, stir in chloroform for 18 hours and filter. Concentrate the resulting solution to the title compound (5.1 g). LC-MS (m/e): 197 (M+1).
後処理
- filtrationFilter the resulting mixture through Celite
- concentrationconcentrate
- stirringstir in chloroform for 18 hours
- filtrationfilter
- concentrationConcentrate the resulting solution to the title compound (5.1 g)
出典と根拠
- ORDレコード
- ord-82d7866b3bb54b5e8ddc37181928f07e
- 出典データセット
- uspto-grants-2010_09
- 特許番号
- US07803938B2
反応ノート
読み込み中…