2,3-Dimethyl-6-nitroquinoxaline → 6-Quinoxalinamine, 2,3-dimethyl-

HRID 1719495ノート

反応式

HRID 1719495 の反応式
[CH3:1][C:2]1[C:11]([CH3:12])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:13]([O-])=O)[CH:8]=2)[N:3]=1.[H][H]>[Pd]>[NH2:13][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([CH3:1])[C:11]([CH3:12])=[N:10]2

参加物

4

反応物 2

HCID 6089992,3-Dimethyl-6-nitroquinoxalineHCID 178418361HCID 178418361、化合物

生成物 1

HCID 1460536-Quinoxalinamine, 2,3-dimethyl-

試薬・触媒・溶媒 1

HCID 23938Palladium触媒

実験手順

A near solution of 2,3-dimethyl-6-nitroquinoxaline (62.9 g, 0.31 mole) in 1 L of absolute alcohol (Mallinkrodt) was hydrogenated in Parr apparatus using 5% Palladium on carbon 50% wet catalyst (Englehard). Hydrogen uptake (100% of theory) in 2 hours was noted. After the reduction stopped the catalyst was removed by filtration and the filtrate remaining concentrated to dryness in vacuo. The residue remaining was used without further purification as an intermediate in part C. Yield 52 g (96%).

後処理

  1. customwas removed by filtration
  2. concentrationthe filtrate remaining concentrated to dryness in vacuo
  3. customThe residue remaining was used without further purification as an intermediate in part C

出典と根拠

ORDレコード
ord-3760b66f7ddb4819b045f7fdcfb7243d
出典データセット
uspto-grants-1985_09
特許番号
US04540693

反応ノート

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