Ethanol → HCID 13374891、化合物

HRID 1719617ノート

反応式

HRID 1719617 の反応式
[C:1]1([C:7]2[S:8][C:9]3[C:14]([C:15](=[O:17])[CH:16]=2)=[CH:13][CH:12]=[CH:11][C:10]=3C=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:20]([O:26][CH2:27][CH2:28][CH2:29][CH3:30])(=[O:25])[CH2:21][C:22]([CH3:24])=O.[NH2:31]/[C:32](/[CH3:36])=[CH:33]\[C:34]#[N:35].[CH2:37](O)C>>[C:34]([C:33]1[CH:37]([C:10]2[CH:11]=[CH:12][CH:13]=[C:14]3[C:9]=2[S:8][C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[CH:16][C:15]3=[O:17])[C:21]([C:20]([O:26][CH2:27][CH2:28][CH2:29][CH3:30])=[O:25])=[C:22]([CH3:24])[NH:31][C:32]=1[CH3:36])#[N:35]

参加物

5

反応物 4

HCID 702EthanolHCID 11576Butyl acetoacetateHCID 5325263(2Z)-3-Amino-2-butenenitrileHCID 133748414-Oxo-2-phenyl-4H-1-benzothiopyran-8-carbaldehyde

生成物 1

HCID 13374891HCID 13374891、化合物

実験手順

10 mmol each of 2-phenyl-4-oxo-4H-thiochromen-8-aldehyde, butyl acetoacetate and 3-aminocrotononitrile were boiled under reflux in 30 ml of ethanol overnight, the mixture was concentrated and the residue was crystallized with ethyl acetate.

後処理

  1. concentrationthe mixture was concentrated
  2. customthe residue was crystallized with ethyl acetate

出典と根拠

ORDレコード
ord-0bd9546d4eb94ed090e82e474ebaa98f
出典データセット
uspto-grants-1985_09
特許番号
US04540789

反応ノート

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