Benzoyl Peroxide → 1-(Bromomethyl)-4-fluoro-2-nitrobenzene
反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1.[Br:12]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][Br:12])=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1参加物
5
実験手順
To a stirred solution of 4-fluoro-2-nitro toluene (48.9 g) and N-bromosuccinimide (56 g) in carbon tetrachloride (300 ml) was added benzoylperoxide (0.78 g). The mixture was heated under reflux for 90 minutes. Additionally, benzoylperoxide (0.78 g) was added to the mixture. Reflux was continued 90 minutes then, cooled to room temperature.
後処理
- temperatureThe mixture was heated
- temperatureunder reflux for 90 minutes
- temperatureReflux
出典と根拠
- ORDレコード
- ord-75f22451642547eba7d5a1a1f12a4943
- 出典データセット
- uspto-grants-1996_04
- 特許番号
- US05504095
反応ノート
読み込み中…