Sodium Sulfite → HCID 86749374、化合物
反応式
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Br)=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.[S:13]([O-:16])([O-:15])=[O:14].[Na+:17].[Na+]>O>[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][S:13]([O-:16])(=[O:15])=[O:14])=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.[Na+:17]参加物
4
実験手順
A solution of 4-fluoro-2-nitrobenzylbromide (50.1 g) and sodium sulfite (27.3 g) in water (200 ml) was heated under reflux for 2.5 hours and cooled to room temperature. The solvent was removed under reduced pressure and ethanol (100 ml) was added to the crude product.
後処理
- temperatureunder reflux for 2.5 hours
- customThe solvent was removed under reduced pressure and ethanol (100 ml)
- additionwas added to the crude product
出典と根拠
- ORDレコード
- ord-d2b5e084fb4946508147eb1d65cfcb51
- 出典データセット
- uspto-grants-1996_04
- 特許番号
- US05504095
反応ノート
読み込み中…