Oxalyl chloride → 1,2,3,4-Tetrahydronaphthalene-2-carbonyl chloride
反応式
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[C:11]([OH:13])=O.C(Cl)(=O)C([Cl:17])=O>C1(C)C=CC=CC=1>[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH:2]1[C:11]([Cl:17])=[O:13]参加物
4
反応条件
- 温度
- 50 °C
実験手順
The suspension of 1,2,3,4-tetrahydro-2-naphthoic acid (500 mg, 2.84 mmol) in 5 ml of toluene was treated with oxalyl chloride (720 mg, 5.675 mmol). The mixture was stirred at 50° C. for 5 hrs. All volatile materials were removed in vacuo and product 1,2,3,4-Tetrahydro-2-naphthoyl chloride was obtained as a colorless oil, which was used for next step reaction without further purification.
後処理
- customAll volatile materials were removed in vacuo
出典と根拠
- ORDレコード
- ord-8b24b32b0c1740e8afae0c7f0c1cb18a
- 出典データセット
- uspto-grants-1996_04
- 特許番号
- US05508306
反応ノート
読み込み中…