Hydroxylamine → Carbamic acid, hydroxy-, butyl ester

HRID 1721485ノート

反応式

HRID 1721485 の反応式
S([O-])([O-])(=O)=O.[NH2:6][OH:7].Cl[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH3:15])=[O:10].[OH-].[Na+]>>[OH:7][NH:6][C:9](=[O:10])[O:11][CH2:12][CH2:13][CH2:14][CH3:15]

参加物

5

反応物 4

HCID 787HydroxylamineHCID 1117Sulfate IonHCID 14798Sodium HydroxideHCID 61140Butyl chloroformate

生成物 1

HCID 164691Carbamic acid, hydroxy-, butyl ester

実験手順

With respect to butyl N,O-dimethylcarbamate, a process disclosed in the specification of West German Patent Application Laid-open No. 3,245,503 is known. This process comprises reacting sulfate of hydroxylamine as a starting material with butyl chloroformate in the presence of sodium hydroxide, extracting the reaction product with dichloromethane, drying the extract, distilling the solvent away from the dried extract to obtain butyl hydroxycarbamate and dimethylating this product using dimethyl sulfate and a sodium hydroxide solution to obtain ethyl N,O-dimethylhydroxycarbamate in the total yield of 65%.

後処理

  1. extractionextracting the reaction product with dichloromethane
  2. customdrying the extract
  3. distillationdistilling the solvent away from the dried
  4. extractionextract

出典と根拠

ORDレコード
ord-f9be280d60b6463ebc14cd7f5a4e6742
出典データセット
uspto-grants-1996_04
特許番号
US05510511

反応ノート

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