Phenylacetylene → (Bromoethynyl)benzene

HRID 1722226ノート

反応式

HRID 1722226 の反応式
[OH-].[Na+].[Br:3]Br.[C:5]1([C:11]#[CH:12])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>O>[C:5]1([C:11]#[C:12][Br:3])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

参加物

5

反応物 3

HCID 10821PhenylacetyleneHCID 14798Sodium HydroxideHCID 24408Bromine

生成物 1

HCID 136737(Bromoethynyl)benzene

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

A solution of sodium hydroxide (31.4 g) in water (160 ml) was cooled to 6° C. and bromine (18 ml) was added dropwise, the temperature being kept below 20° C. Phenylacetylene (20 g) in dimethoxethylene (80 ml) was added over 15 minutes and the mixture was stirred at room temperature for 5 hours. Water (200 ml) was added, and the mixture was extracted with ether (4×60 ml), dried (MgSO4) and the solvents removed at room temperature to yield phenylbromoacetylene.

後処理

  1. custombeing kept below 20° C
  2. extractionthe mixture was extracted with ether (4×60 ml)
  3. dry with materialdried (MgSO4)
  4. customthe solvents removed at room temperature

出典と根拠

ORDレコード
ord-3f44a5abe6ca460cad2e775594c2884e
出典データセット
uspto-grants-1989_08
特許番号
US04855086

反応ノート

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