Methanesulfonyl chloride → HCID 13603621、化合物
反応式
[CH3:1][O:2][C:3]1[CH:15]=[CH:14][CH:13]=[CH:12][C:4]=1[O:5][CH2:6][CH:7]1[NH:11][CH2:10][CH2:9][S:8]1.[CH3:16][S:17](Cl)(=[O:19])=[O:18]>N1C=CC=CC=1.OS(O)(=O)=O>[CH3:16][S:17]([N:11]1[CH2:10][CH2:9][S:8][CH:7]1[CH2:6][O:5][C:4]1[CH:12]=[CH:13][CH:14]=[CH:15][C:3]=1[O:2][CH3:1])(=[O:19])=[O:18]参加物
5
実験手順
A solution of 2-(o-methoxyphenoxy)methyl-thiazolidine (1.83 g) in pyridine (6 ml) is treated with methane sulphonyl chloride (1.2 g) at room temperature. After 4 hours the mixture is diluted with 2N H2SO4, extracted with Et2O, to afford after the usual work-up 2.2 g of 3-methanesulphonyl-2-(o-methoxyphenoxy)methyl-thiazolidine m.p. 118°-120° C.
後処理
- extractionextracted with Et2O
出典と根拠
- ORDレコード
- ord-b604238656cf439e8cade8f13ebf50be
- 出典データセット
- uspto-grants-1989_08
- 特許番号
- US04857643
反応ノート
読み込み中…