Dimethylformamide → 2-Chloro-7,7-difluoro-9-(4-methoxy-benzyl)-5-methyl-5,7,8,9-tetrahydro-pyrimido[4,5-b][1,4]diazepin-6-one

反応式

[C:25](=[O:26])([O-:27])[O-:28].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:24]1)[N:7]([CH2:15][c:16]1[cH:17][cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]1)[CH2:8][C:9]([F:13])([F:14])[C:10](=[O:12])[NH:11]2.[Cs+:29].[Cs+:30].[I:31][CH3:32]>>[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:24]1)[N:7]([CH2:15][c:16]1[cH:17][cH:18][c:19]([O:22][CH3:23])[cH:20][cH:21]1)[CH2:8][C:9]([F:13])([F:14])[C:10](=[O:12])[N:11]2[CH3:25]