関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Pyridine | HCID 1049 | — |
| 反応物 | Cetyl Alcohol | HCID 2682 | — |
| 反応物 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-Hexadecanol, 1-(4-methylbenzenesulfonate) | HCID 80171 | — |
反応手順
10 mmol palmityl alcohol and 20 mmol pyridine are dissolved in 100 ml dry dichloromethane. 10 mmol toluene4-sulphonyl chloride is slowly added and the mixture is heated to 40° C. with stirring for 1 hour. The reaction is cooled to room temperature and 25 ml cold water is added to stop the reaction. The mixture is washed with 3×50 ml cold, 1% aqueous sulfuric acid to remove the pyridine followed by 3×25 ml cold water and evaporation to yield palmityl toluene-4-sulfonate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07491836B2 |
|---|
| 出典データセット | uspto-grants-2009_02 |
|---|
| ORD ID | ord-5b5ffbafb1774ba4832954975dc33a2e |
|---|
| 出典メモ | uspto-grants-2009_02 |
|---|
