反应详情

温度

40 °C

10 mmol palmityl alcohol and 20 mmol pyridine are dissolved in 100 ml dry dichloromethane. 10 mmol toluene4-sulphonyl chloride is slowly added and the mixture is heated to 40° C. with stirring for 1 hour. The reaction is cooled to room temperature and 25 ml cold water is added to stop the reaction. The mixture is washed with 3×50 ml cold, 1% aqueous sulfuric acid to remove the pyridine followed by 3×25 ml cold water and evaporation to yield palmityl toluene-4-sulfonate.

1. temperatureThe reaction is cooled to room temperature
2. customthe reaction
3. washThe mixture is washed with 3×50 ml cold
4. custom1% aqueous sulfuric acid to remove the pyridine
5. customfollowed by 3×25 ml cold water and evaporation