Benzaldehyde → 3-Benzylidene-6-chloroindolin-2-one
反応式
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][C:7](=[O:11])[NH:8]2)=[CH:4][CH:3]=1.[CH:12](=O)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.N1CCCC1>CO>[CH:12](=[C:6]1/[C:7](=[O:11])[NH:8][C:9]2[C:5]/1=[CH:4][CH:3]=[C:2]([Cl:1])[CH:10]=2)/[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1参加物
5
実験手順
In a manner similar to the method described in example 1a, 6-chlorooxindole (1.0 g, 5.7 mmol) was reacted with benzaldehyde (0.6 g, 5.7 mmol) (Aldrich) and pyrrolidine (0.4 g, 5.7 mmol) in methanol to give a mixture of E- and Z-3-benzylidene-6-chloro-1,3-dihydro-indol-2-one as a yellow solid (Yield 1.5 g, 100%).
後処理
- customto give
出典と根拠
- ORDレコード
- ord-6ed43f39301540479e32a3e2acfb7e23
- 出典データセット
- uspto-grants-2009_02
- 特許番号
- US07495007B2
反応ノート
読み込み中…