Acetic Anhydride → N-(2-(Pyridin-2-yl)ethyl)acetamide
反応式
[NH2:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][N:5]=1.[C:10](OC(=O)C)(=[O:12])[CH3:11]>CN(C)C1C=CN=CC=1.N1C=CC=CC=1>[N:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[CH2:3][CH2:2][NH:1][C:10](=[O:12])[CH3:11]参加物
5
実験手順
The title compound is prepared by the procedure of Example 12 using 25 g of 2-(2-aminoethyl)pyridine, 22.2 ml of acetic anhydride, 2.57 g of 4-dimethylaminopyridine and 100 ml of pyridine. The residue is purified by column chromatography (silica gel:20% methyl alcohol/ethyl acetate) to give 7.5 g of desired product as a yellow oil.
後処理
- customThe residue is purified by column chromatography (silica gel:20% methyl alcohol/ethyl acetate)
出典と根拠
- ORDレコード
- ord-3408b798c68b48f581c2bc9f130cf1ea
- 出典データセット
- uspto-grants-1994_07
- 特許番号
- US05328921
反応ノート
読み込み中…