Methyl iodide → 2-[[Acetyl[4-methoxy-3-(tetradecyloxy)benzoyl]-amino]methyl]-1-methylpyridinium iodide

反応式

[C:1]([N:4]([CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][N:32]=1)[C:5](=[O:29])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:7]=1)(=[O:3])[CH3:2].[CH3:37][I:38]>>[I-:38].[C:1]([N:4]([CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][N+:32]=1[CH3:37])[C:5](=[O:29])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:7]=1)(=[O:3])[CH3:2]

参加物

反応物 2

HCID 6328Methyl iodide

HCID 10255296N-Acetyl-4-methoxy-3-(tetradecyloxy)-N-(2-pyridinylmethyl)benzamide

生成物 1

HCID 99865782-[[Acetyl[4-methoxy-3-(tetradecyloxy)benzoyl]-amino]methyl]-1-methylpyridinium iodide

実験手順

The title compound is prepared by the procedure of Example 28 using 0.421 g of product from Example 44 and 2.64 ml of methyl iodide. The residue is recrystallized from methyl alcohol to give 0.541 g of the desired product as yellow crystals.

後処理

customThe residue is recrystallized from methyl alcohol

出典と根拠

ORDレコード: ord-5b37b50c4a9e4c7ab3e4cb805d6bd2d2
出典データセット: uspto-grants-1994_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05328921

反応ノート

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