Oxalyl chloride → 3,4-Bis(heptyloxy)benzoyl chloride

HRID 1728881ノート

反応式

HRID 1728881 の反応式
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[O:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[C:12](O)=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].C(Cl)(=O)C([Cl:29])=O>C(Cl)Cl.CN(C)C=O>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[O:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[C:12]([Cl:29])=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

参加物

5

反応物 2

HCID 65578Oxalyl chlorideHCID 190152233,4-Bis(heptyloxy)benzoic acid

生成物 1

HCID 190151863,4-Bis(heptyloxy)benzoyl chloride収率 100.1%

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6344Dichloromethane溶媒

実験手順

To a room temperature mixture of 5 g of product from Example 110 in 80 ml of methylene chloride and 5 drops of dimethylformamide is added 2.72 g of oxalyl chloride. The reaction is stirred at room temperature for 2.5 days and concentrated in vacuo. The residue is dissolved in diethyl ether, passed through a pad of diatomaceous earth and concentrated in vacuo to give 5.27 g of the desired product as colorless crystals.

後処理

  1. concentrationconcentrated in vacuo
  2. dissolutionThe residue is dissolved in diethyl ether
  3. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-e2be4dcb347841b59f1334793b18662e
出典データセット
uspto-grants-1994_07
特許番号
US05328921

反応ノート

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