Oxalyl chloride → 4-(Decyloxy)-3-(1,1-dimethylethyl)benzoyl chloride

HRID 1728894ノート

反応式

HRID 1728894 の反応式
[CH2:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][C:13]=1[C:21]([CH3:24])([CH3:23])[CH3:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].C(Cl)(=O)C([Cl:28])=O>C(Cl)Cl.CN(C)C=O>[CH2:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([Cl:28])=[O:17])=[CH:14][C:13]=1[C:21]([CH3:24])([CH3:23])[CH3:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

参加物

5

反応物 2

HCID 65578Oxalyl chlorideHCID 19015379HCID 19015379、化合物

生成物 1

HCID 190152784-(Decyloxy)-3-(1,1-dimethylethyl)benzoyl chloride

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6344Dichloromethane溶媒

実験手順

To 3.0 g of product from Example 131 in 30 ml of methylene chloride plus 2 drops of dimethylformamide is added 2.0 ml of oxalyl chloride via syringe. The reaction is stirred at room temperature for 18 hours, concentrated in vacuo, dissolved in diethyl ether and filtered through a pad of diatomaceous earth. The diethyl ether is concentrated in vacuo to give 3.15 g of the desired product as a yellow oil.

後処理

  1. concentrationconcentrated in vacuo
  2. dissolutiondissolved in diethyl ether
  3. filtrationfiltered through a pad of diatomaceous earth
  4. concentrationThe diethyl ether is concentrated in vacuo

出典と根拠

ORDレコード
ord-524508adfbcf48e293fe47c8c6cef590
出典データセット
uspto-grants-1994_07
特許番号
US05328921

反応ノート

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