Methyl iodide → 1-Methyl-2-[[[(4-methylphenyl)sulfonyl][[3-(tetradecyloxy)phenyl]methyl]amino]methyl]pyridinium iodide
反応式
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]([CH2:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][N:36]=2)[CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH:14]=2)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH3:41][I:42]>>[I-:42].[CH3:41][N+:36]1[CH:37]=[CH:38][CH:39]=[CH:40][C:35]=1[CH2:34][N:11]([S:8]([C:5]1[CH:6]=[CH:7][C:2]([CH3:1])=[CH:3][CH:4]=1)(=[O:10])=[O:9])[CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH:14]=1参加物
3
反応条件
- 温度
- 100 °C
実験手順
A mixture of 1.01 g of product from Example 80 and 12.69 g of methyl iodide is heated, in a sealed tube, at 100° C. for 5 hours. The reaction is concentrated to give 1.17 g of the desired product as a yellow-green foam.