Methyl iodide → HCID 53635658、化合物

反応式

[CH3:1][C:2]([C:25]([O:27][CH3:28])=[O:26])([CH2:17][C:18]1[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][CH:19]=1)[NH:3][C:4]([O:6][CH:7]1[CH:14]2[CH2:15][CH:10]3[CH2:11][CH:12]([CH2:16][CH:8]1[CH2:9]3)[CH2:13]2)=[O:5].[C:29](=O)([O-])[O-].[K+].[K+].IC>>[CH3:29][O:24][C:21]1[CH:20]=[CH:19][C:18]([CH2:17][C:2]([CH3:1])([C:25]([O:27][CH3:28])=[O:26])[NH:3][C:4]([O:6][CH:7]2[CH:8]3[CH2:16][CH:12]4[CH2:11][CH:10]([CH2:15][CH:14]2[CH2:13]4)[CH2:9]3)=[O:5])=[CH:23][CH:22]=1

参加物

反応物 3

HCID 6328Methyl iodide

HCID 11430Potassium Carbonate

HCID 54546551HCID 54546551、化合物

生成物 1

HCID 53635658HCID 53635658、化合物

実験手順

The title compound was prepared from methyl α-methyl-N-[(tricyclo[3.3.1.13,7 ]dec-2-yloxy)carbonyl]-DL-tyrosinate (0.671 g, 0.0017 mmol, prepared usingthe procedure described in Example 47, Step A), potassium carbonate (0.345 g, 0.0025 mmol) and iodomethane (0.368 g, 0.0025 mol) using the procedure described in Example 47, Step B. MS: 402.4 (MH+).

後処理

customprepared usingthe procedure

出典と根拠

ORDレコード: ord-ed91aaf59da7444c9518261f37f98c1b
出典データセット: uspto-grants-1994_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05331006

反応ノート

読み込み中…