1,2-Dibromoethane → Hydrogen Bromide
反応式
[NH2:1][C:2]1[N:3]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[Br:17][CH2:18][CH2:19]Br>C1(C)C=CC=CC=1>[C:11]1([N:3]2[C:4]3[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=3[N:6]3[CH2:18][CH2:19][N:1]=[C:2]23)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[BrH:17]参加物
5
実験手順
A solution of 2-amino-3-phenylbenzimidazole (4.18 g., 0.02 mole) and 1,2-dibromoethane (7.52 g., 0.04 mole) in toluene (40 ml.) was heated under reflux for 24 hours. After removal of the solvent the residual oil was crystallised from ethanol/ether. The product (0.950 g.) was recrystallised from ethanol/ether to give the title compound as its hydrobromide (0.875 g., m.p. 225°-228° C).
後処理
- temperatureunder reflux for 24 hours
- customAfter removal of the solvent the residual oil
- customwas crystallised from ethanol/ether
- customThe product (0.950 g.) was recrystallised from ethanol/ether
出典と根拠
- ORDレコード
- ord-98646f4f10034ccdaf0d991b5cc35b2e
- 出典データセット
- uspto-grants-1976_11
- 特許番号
- US03989709
反応ノート
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