Water → 1-(Cyanoamino)nonan-4-yl acetate

HRID 1729909ノート

反応式

HRID 1729909 の反応式
[C:1]([O:4][CH:5]([CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH2:6][CH2:7][CH2:8][NH:9][C:10]([NH2:12])=O)(=[O:3])[CH3:2].C1(C)C=CC(S(Cl)(=O)=O)=CC=1.O>N1C=CC=CC=1>[C:1]([O:4][CH:5]([CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH2:6][CH2:7][CH2:8][NH:9][C:10]#[N:12])(=[O:3])[CH3:2]

参加物

5

反応物 3

HCID 962WaterHCID 73974-Toluenesulfonyl chlorideHCID 215014481-(Carbamoylamino)nonan-4-yl acetate

生成物 1

HCID 215014751-(Cyanoamino)nonan-4-yl acetate

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

To a stirred solution of 4-acetoxynonylurea (2.4 g., 0.01 mole) in pyridine (10 ml.) is added p-toluene-sulfonyl chloride (2.0 g., excess) in one portion. The reaction is stirred at room temperature for six hours then poured into water (150 ml.). The aqueous mixture is extracted with ether (3 × 75 ml.), the ether is washed with 5% hydrochloric acid, brine, and dried over sodium sulfate. The solvent is removed in vacuo to give 4-acetoxynonylcyanamide as a residual oil.

後処理

  1. extractionThe aqueous mixture is extracted with ether (3 × 75 ml.)
  2. washthe ether is washed with 5% hydrochloric acid, brine
  3. dry with materialdried over sodium sulfate
  4. customThe solvent is removed in vacuo

出典と根拠

ORDレコード
ord-88c125c3ae62404296102bc7e732935a
出典データセット
uspto-grants-1976_11
特許番号
US03989749

反応ノート

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