Hydrochloric Acid → 3-(1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridin-2-yl)-N-phenylpropionic acid amide

HRID 1730005

反応式

HRID 1730005 の反応式
[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][NH:11][CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2.[C:15]1([NH:21][C:22](=[O:25])[CH:23]=[CH2:24])[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.Cl>>[CH3:1][C:2]1[C:3]2[C:8]([CH:9]3[C:14]=1[CH2:13][CH2:12][N:11]([CH2:24][CH2:23][C:22]([NH:21][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:25])[CH2:10]3)=[CH:7][CH:6]=[CH:5][CH:4]=2

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 221792N-PhenylacrylamideHCID 214987881,3,4,9b-tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine

生成物 1

HCID 681390553-(1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridin-2-yl)-N-phenylpropionic acid amide

実験手順

1,3,4,9b-Tetrahydro-5-methyl-2H-indeno[1,2-c]pyridine and N-phenyl acrylamide are reacted in accordance with the process described in Example 6. Reaction period 4 hours. M.P. of the hydrochloride of the title compound 207°-209° from 95% ethanol.

後処理

  1. customReaction period 4 hours

出典と根拠

ORDレコード
ord-dfd3edd2b6e24ecda950bbbca3bb4bba
出典データセット
uspto-grants-1976_11
特許番号
US03991066

関連ノート

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