化工社化工社 化学情報印刷レポート · 研究参考用
1-Chloro-amitriptyline → Amitriptyline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Chloro-amitriptyline | HCID 103696 | — |
| 反応物 | D-Tartaric acid | HCID 439655 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Amitriptyline | HCID 2160 | — |
反応手順
1-Chloro-amitriptyline (196 mg) in 3 ml. absolute ethanol was added to an ethanolic solution of 1.1 eq. d-tartaric acid and warmed for 5-10 mins. The title compound was precipitated with ethyl ether as a white powder. After purity and identification checks, the overall yield from amitriptyline base was 32%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03991103 |
| 出典データセット | uspto-grants-1976_11 |
| ORD ID | ord-b196b6985ee74a0ebcf6527350330854 |
| 出典メモ | uspto-grants-1976_11 |