Chloroform → HCID 54205117、化合物

HRID 1730307ノート

反応式

HRID 1730307 の反応式
[C:1]1([N:7]2[C:11](=[NH:12])[C:10](=[O:13])[N:9]([CH3:14])[C:8]2=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:16]=[CH:17][C:18]([Cl:21])([Cl:20])[Cl:19].C(Cl)(Cl)[Cl:23]>>[C:1]1([N:7]2[C:11](=[N:12][C:17]([OH:16])([Cl:23])[C:18]([Cl:21])([Cl:20])[Cl:19])[C:10](=[O:13])[N:9]([CH3:14])[C:8]2=[O:15])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 6212ChloroformHCID 6407ChloralHCID 214974605-Imino-3-methyl-1-phenylimidazolidine-2,4-dione

生成物 1

HCID 54205117HCID 54205117、化合物

反応条件

温度
20 °C

実験手順

1-phenyl-3-methyl-5-iminoimidazolidine-2,4-dione (15.0 g -- 0.074 mol) was slurried in 40 ml chloroform. Chloral (21.8 g -- 0.148 mol) was added directly to the slurry. Exothermicity raised the temperature 20° C.The reaction mixture was momentarily homogeneous before an abundance of product precipitated. An additional 100 ml of chloroform was added at thispoint. After 0.5 hour the mixture was filtered. The filter cake was washed with chloroform and dried. The product melted at 130°-133° C.

後処理

  1. customprecipitated
  2. additionAn additional 100 ml of chloroform was added at thispoint
  3. filtrationAfter 0.5 hour the mixture was filtered
  4. washThe filter cake was washed with chloroform
  5. customdried

出典と根拠

ORDレコード
ord-219a48721f5f443cb6d2e9a182aef157
出典データセット
uspto-grants-1976_11
特許番号
US03992402

反応ノート

読み込み中…