化工社化工社 化学情報印刷レポート · 研究参考用
Cyclohexylamine → N-Cyclohexylacetoacetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclohexylamine | HCID 7965 | — |
| 反応物 | Diketene | HCID 12661 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | N-Cyclohexylacetoacetamide | HCID 70805 | — |
反応手順
A solution of diketene (42 g.) in benzene (74 ml.) is added dropwise with vigorous stirring to a solution of cyclohexylamine (49.6 g.) in benzene (125 ml.). The rate of addition is adjusted so that a gentle reflux is maintained. The benzene is removed under vacuum and the yellow oil crystallizes upon trituation with hexane. A yield of 88.7 g. of product melting at 66°-69° C. is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03993637 |
| 出典データセット | uspto-grants-1976_11 |
| ORD ID | ord-f41e8808f013472d95e642b7057a0f3c |
| 出典メモ | uspto-grants-1976_11 |