反应详情

A solution of diketene (42 g.) in benzene (74 ml.) is added dropwise with vigorous stirring to a solution of cyclohexylamine (49.6 g.) in benzene (125 ml.). The rate of addition is adjusted so that a gentle reflux is maintained. The benzene is removed under vacuum and the yellow oil crystallizes upon trituation with hexane. A yield of 88.7 g. of product melting at 66°-69° C. is obtained.

1. additionThe rate of addition
2. temperaturea gentle reflux
3. temperatureis maintained
4. customThe benzene is removed under vacuum
5. customthe yellow oil crystallizes upon trituation with hexane