Pyridine → 2-Decynyl cyclopropanecarboxylate

HRID 1731212

反応式

HRID 1731212 の反応式
[CH2:1]([OH:11])[C:2]#[C:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].N1C=CC=CC=1.[CH:18]1([C:21](Cl)=[O:22])[CH2:20][CH2:19]1>CCOCC>[CH:18]1([C:21]([O:11][CH2:1][C:2]#[C:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])=[O:22])[CH2:20][CH2:19]1

参加物

5

反応物 3

HCID 1049PyridineHCID 77637Cyclopropanecarbonyl chlorideHCID 777632-Decyn-1-ol

生成物 1

HCID 214954152-Decynyl cyclopropanecarboxylate

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒

実験手順

To a solution of 3.85 g. of 2-decyn-1-ol and 3.95 g. of pyridine in 100 ml. ether is added 3.0 g. of cyclopropanecarboxylic acid chloride. The mixture is stirred overnight under nitrogen. The reaction mixture is poured into distilled water, washed with dilute hydrochloric acid and then with sodium bicarbonate and solvent removed to yield 2-decynyl cyclopropanecarboxylate, b.p. 96°-97° (bath) at 0.1 mm.

後処理

  1. additionThe reaction mixture is poured
  2. distillationinto distilled water
  3. washwashed with dilute hydrochloric acid
  4. customwith sodium bicarbonate and solvent removed

出典と根拠

ORDレコード
ord-e0af6a6589f043c7bce89d0001b10d60
出典データセット
uspto-grants-1976_11
特許番号
US03995054

関連ノート

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