Z-Thr(But)-Ser(But)-OMe → H-Thr(But)-Ser(But)-OMe

HRID 1731232ノート

反応式

HRID 1731232 の反応式
[NH:1](C(OCC1C=CC=CC=1)=O)[C@H:2]([C:10]([NH:12][C@H:13]([C:20]([O:22][CH3:23])=[O:21])[CH2:14][O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:11])[C@@H:3]([CH3:9])[O:4][C:5]([CH3:8])([CH3:7])[CH3:6]>C(OCC)(=O)C.[Pd]>[NH2:1][C@H:2]([C:10]([NH:12][C@H:13]([C:20]([O:22][CH3:23])=[O:21])[CH2:14][O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:11])[C@@H:3]([CH3:9])[O:4][C:5]([CH3:8])([CH3:7])[CH3:6]

参加物

4

反応物 1

HCID 131710554Z-Thr(But)-Ser(But)-OMe

生成物 1

HCID 131710555H-Thr(But)-Ser(But)-OMe

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

3.27 g of Z-Thr(But)-Ser(But)-OMe in 50 ml of ethyl acetate are hydrogenated in the presence of 0.5 g of palladium on charcoal (10% strength). After the absorption of hydrogen has ceased (1 hour), the catalyst is filtered off and the solution is evaporated. The product, which is obtained as an oil, is a single substance according to thin layer chromatography.

後処理

  1. customAfter the absorption of hydrogen
  2. custom(1 hour)
  3. filtrationthe catalyst is filtered off
  4. customthe solution is evaporated
  5. customThe product, which is obtained as an oil

出典と根拠

ORDレコード
ord-8d1aeb1e520c44deaaf2c3e697668463
出典データセット
uspto-grants-1976_11
特許番号
US03994871

反応ノート

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