Hydrochloric Acid → HCID 19739392、化合物

HRID 1731455ノート

反応式

HRID 1731455 の反応式
C1CO[CH:3]([CH2:4][CH2:5][CH2:6][C:7]2[CH:14]=[CH:13][C:10]([C:11]#[N:12])=[CH:9][CH:8]=2)[O:2]1.O1CCCC1.Cl>O>[C:11]([C:10]1[CH:13]=[CH:14][C:7]([CH2:6][CH2:5][CH2:4][CH:3]=[O:2])=[CH:8][CH:9]=1)#[N:12]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 10856924HCID 10856924、化合物

生成物 1

HCID 19739392HCID 19739392、化合物収率 116.5%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 2.8 g of p-(4,4-ethylenedioxybutyl)benzonitrile, 56 ml of tetrahydrofuran and 56 ml of 10% hydrochloric acid was stirred for 3 hours at room temperature and then left to stand overnight. Thereafter, the reaction mixture was diluted with water and extracted three times with diethyl ether. The organic phases were washed twice with water, dried over magnesium sulphate, filtered and concentrated. There were obtained 2.6 g of 4-(p-cyanophenyl)butyraldehyde which was processed without additional purification.

後処理

  1. waitleft
  2. waitto stand overnight
  3. extractionextracted three times with diethyl ether
  4. washThe organic phases were washed twice with water
  5. dry with materialdried over magnesium sulphate
  6. filtrationfiltered
  7. concentrationconcentrated

出典と根拠

ORDレコード
ord-65f78fed37314ea4b5037e2422b3b91c
出典データセット
uspto-grants-1986_11
特許番号
US04621901

反応ノート

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