Ammonia → N-Dodecylacrylamide

HRID 1732233

反応式

HRID 1732233 の反応式
CO[CH2:3][CH2:4][C:5]([NH2:7])=[O:6].[CH2:8](N)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19].N.[OH-].[Na+]>>[CH2:19]([NH:7][C:5](=[O:6])[CH:4]=[CH2:3])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH3:8]

参加物

5

反応物 4

HCID 222AmmoniaHCID 13583DodecylamineHCID 14798Sodium HydroxideHCID 52524813-Methoxypropanamide

生成物 1

HCID 73929N-Dodecylacrylamide

実験手順

103.1 g (1.0 mole) of 3-methoxypropionamide are heated with 194.6 g (1.05 mole) of dodecylamine in a temperature range of 130°-170° C. until the evolution of ammonia is complete. The mixture is allowed to cool, 1.5 g of sodium hydroxide is added and the mixture is heated in a high vacuum at 90° to 110° C. The methanol is split off within about 30 minutes, vigorous foaming occurring. The temperature is increased and 172.4 g (0.72 mole=72% of the theoretical yield) of N-dodecylacrylamide having a Bp0.1 of 165°-170° C., which solidifies into crystalline form in the receiver, are distilled off.

後処理

  1. temperatureto cool
  2. temperaturethe mixture is heated in a high vacuum at 90° to 110° C
  3. customThe methanol is split off within about 30 minutes
  4. temperatureThe temperature is increased

出典と根拠

ORDレコード
ord-9eeb117b26d644288205284e326532bc
出典データセット
uspto-grants-1980_12
特許番号
US04237067

関連ノート

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