Potassium Hydroxide → Phosphorothioic acid, O,O-dipropyl ester, potassium salt
反応式
[CH2:1]([O:4][P:5](Cl)([O:7][CH2:8][CH2:9][CH3:10])=[S:6])[CH2:2][CH3:3].[OH-:12].[K+:13]>C(O)CC>[K+:13].[P:5]([O-:12])([O:7][CH2:8][CH2:9][CH3:10])([O:4][CH2:1][CH2:2][CH3:3])=[S:6]参加物
4
実験手順
To 100 g (460 mmole) of di-n-propylchlorothiophosphate in 300 ml of 1-propanol was added 58.8 g (920 mmole) of 88% potassium hydroxide pellets. The reaction mixture was refluxed overnight and then cooled to room temperature. The precipitated potassium chloride was filtered off and the solvent was stripped in vacuo. The resulting solid was slurried in 20% diethyl ether/80% hexanes and filtered yielding 67 g of the title compound, a fluffy white solid, mp 205°-207° C.
後処理
- temperatureThe reaction mixture was refluxed overnight
- filtrationThe precipitated potassium chloride was filtered off
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-a219393743ee4290a039167c82c28f83
- 出典データセット
- uspto-grants-1996_07
- 特許番号
- US05536710
反応ノート
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