Aluminium lithium hydride → 1H-Pyrrolo[2,3-b]pyridine-1-ethanol
反応式
[N:1]1([CH2:10][C:11](OC)=[O:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][N:8]=2)[CH:3]=[CH:2]1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[N:1]1([CH2:10][CH2:11][OH:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][N:8]=2)[CH:3]=[CH:2]1参加物
4
実験手順
A procedure similar to that described in Preparation 2 was repeated, except that 7.50 g of methyl 7-azaindol-1-acetate (prepared as described in Preparation 17), 1.80 g of lithium aluminum hydride and 260 ml of anhydrous tetrahydrofuran were used, to give 5.57 g of the title compound, melting at 52.7-53.3° C.
後処理
- customA procedure similar to that described in Preparation 2
出典と根拠
- ORDレコード
- ord-772c43b8732849ae89a37e279f6738c8
- 出典データセット
- uspto-grants-1999_10
- 特許番号
- US05962470
反応ノート
読み込み中…