6-Isopropoxy-2-methylamino-3-nitropyridine → 6-Isopropoxy-N2-methylpyridine-2,3-diamine
反応式
[CH:1]([O:4][C:5]1[N:10]=[C:9]([NH:11][CH3:12])[C:8]([N+:13]([O-])=O)=[CH:7][CH:6]=1)([CH3:3])[CH3:2]>CO.[Pd]>[NH2:13][C:8]1[C:9]([NH:11][CH3:12])=[N:10][C:5]([O:4][CH:1]([CH3:2])[CH3:3])=[CH:6][CH:7]=1参加物
4
実験手順
A procedure similar to that described in Example 6 was repeated, except that 2.38 g of 6-isopropoxy-2-methylamino-3-nitropyridine (prepared as described in Preparation 100) were hydrogenated in 50 ml of methanol in the presence of 0.50 g of 10% w/w palladium-on-charcoal. After working up the product as described in Example 6, 2.00 g of the title compound having Rf=0.62 (on silica gel thin layer chromatography using ethyl acetate as the developing solvent) were obtained.
出典と根拠
- ORDレコード
- ord-3039a420b32244519e571610afec8ba9
- 出典データセット
- uspto-grants-1999_10
- 特許番号
- US05962470
反応ノート
読み込み中…