Methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate → Methyl 3-carboxymethoxy-5-hydroxybenzoate

HRID 1740316ノート

反応式

HRID 1740316 の反応式
C([O:8][C:9]([CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:20]=[C:21]([OH:23])[CH:22]=1)[C:16]([O:18][CH3:19])=[O:17])=[O:10])C1C=CC=CC=1>[Pd].CO>[C:9]([CH2:11][O:12][C:13]1[CH:14]=[C:15]([CH:20]=[C:21]([OH:23])[CH:22]=1)[C:16]([O:18][CH3:19])=[O:17])([OH:10])=[O:8]

参加物

4

反応物 1

HCID 21838035Methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate

生成物 1

HCID 11253108Methyl 3-carboxymethoxy-5-hydroxybenzoate収率 103.5%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

10% palladium on carbon (0.1 g) was added to a mixture of methyl 3-benzyloxycarbonylmethoxy-5-hydroxybenzoate (1 g) in methanol (20 ml) and the mixture was subjected to catalytic reduction at ambient temperature under atmospheric pressure. The catalyst was removed by filtration and the filtrate was evaporated in vacuo to give methyl 3-carboxymethoxy-5-hydroxybenzoate (0.74 g).

後処理

  1. customwas subjected to catalytic reduction at ambient temperature under atmospheric pressure
  2. customThe catalyst was removed by filtration
  3. customthe filtrate was evaporated in vacuo

出典と根拠

ORDレコード
ord-ab7f2c9943814927bc5b195fdfcfcd25
出典データセット
uspto-grants-1999_10
特許番号
US05968985

反応ノート

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