Methanol → (3-Chloropropyl)decyldimethylammonium bromide

HRID 1740343

反応式

HRID 1740343 の反応式
[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH3:3].[Br:14][CH2:15][CH2:16][CH2:17][Cl:18].CO>CCCCCC.C(OC)(C)(C)C>[Br-:14].[Cl:18][CH2:17][CH2:16][CH2:15][N+:2]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])([CH3:1])[CH3:3]

参加物

5

反応物 3

HCID 887MethanolHCID 80061-Bromo-3-chloropropaneHCID 70711N,N-Dimethyl-N-decylamine

生成物 1

HCID 85711137(3-Chloropropyl)decyldimethylammonium bromide

試薬・触媒・溶媒 1

HCID 21982663Methyl t-butylether hexane溶媒

反応条件

温度
65 °C

実験手順

Into a 1000 mL, round-bottomed flask equipped with air condensers and a magnetic stirring plate was charged N,N-dimethyldecylamine (200.0 grams, 1.08 moles), 1-bromo-3-chloropropane (170 grams, 1.08 moles) and methanol (200 mL). The reaction was maintained at 65° C. for 18 hours. Solvent was removed by rotary evaporation under reduced pressure and furthermore with high vacuum distillation to yield brown oil. The oil was placed in a beaker and stirred with hexane/t-butylmethylether 1:1 solution (400 mL) causing a white precipitate. The solids were collected by vacuum filtration. Solids were dried in a vacuum oven at 30° C. overnight. Yield 305.0 grams (0.089 moles, 82%).

後処理

  1. customInto a 1000 mL, round-bottomed flask equipped with air condensers
  2. customSolvent was removed by rotary evaporation under reduced pressure and furthermore with high vacuum distillation
  3. customto yield brown oil
  4. filtrationThe solids were collected by vacuum filtration
  5. customSolids were dried in a vacuum oven at 30° C. overnight

出典と根拠

ORDレコード
ord-d1033feccafd4fd0af23433b4b7180af
出典データセット
uspto-grants-1999_10
特許番号
US05969090

関連ノート

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