Sodium Hydroxide → 1-(2-(2-Propynyloxy)ethyl)piperazine

HRID 1740389ノート

反応式

HRID 1740389 の反応式
[OH-].[Na+].Cl.Cl.[CH2:5]([O:8][CH2:9][CH2:10][N:11]1[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]1)[C:6]#[CH:7]>>[CH2:5]([O:8][CH2:9][CH2:10][N:11]1[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1)[C:6]#[CH:7]

参加物

3

反応物 2

HCID 14798Sodium HydroxideHCID 218386371-(2-(2-Propynyloxy)ethyl)piperazine dihydrochloride

生成物 1

HCID 218386381-(2-(2-Propynyloxy)ethyl)piperazine収率 37.4%

実験手順

To an aqueous solution of 11.83 g of 1-(2-(2-propynyloxy)ethyl)piperazine dihydrochloride (water: 10 mL) was added aqueous sodium hydroxide solution, and the mixture was extracted with ethyl acetate. The organic layer was dried over anhydrous magnesium sulfate and evaporated to give 3.09 g of the title compound.

後処理

  1. extractionthe mixture was extracted with ethyl acetate
  2. dry with materialThe organic layer was dried over anhydrous magnesium sulfate
  3. customevaporated

出典と根拠

ORDレコード
ord-43fb667518ee413291bef76ce4c8c4a7
出典データセット
uspto-grants-1999_10
特許番号
US05969138

反応ノート

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