Ethyl Bromide → 4-Methyl-2-(2,5-dimethylpyrrol-1-yl)-6-propylpyridine

反応式

[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([N:9]2[C:13]([CH3:14])=[CH:12][CH:11]=[C:10]2[CH3:15])[CH:3]=1.Br[CH2:17][CH3:18]>>[CH3:1][C:2]1[CH:7]=[C:6]([CH2:8][CH2:17][CH3:18])[N:5]=[C:4]([N:9]2[C:13]([CH3:14])=[CH:12][CH:11]=[C:10]2[CH3:15])[CH:3]=1

参加物

反応物 2

HCID 6332Ethyl Bromide

HCID 224907362-(2,5-Dimethyl-1H-pyrrol-1-yl)-4,6-dimethylpyridine

生成物 1

HCID 218344104-Methyl-2-(2,5-dimethylpyrrol-1-yl)-6-propylpyridine

実験手順

By analogy to Example 53, Step B, the anion of 4,6-dimethyl-2-(2,5-dimethylpyrrol-1-yl)pyridine was alkylated with bromoethane to give 4-methyl-2-(2,5-dimethylpyrrol-1-yl)-6-propylpyridine.

出典と根拠

ORDレコード: ord-9223c27c6c7b43ccabd18326c6aeae97
出典データセット: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05972975

反応ノート

読み込み中…