Ethylenediamine → N-Cyclohexyl-1,2-ethanediamine

HRID 1742179ノート

反応式

HRID 1742179 の反応式
[C:1]1(=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:8]([NH2:11])[CH2:9][NH2:10]>C(O)C.O=[Pt]=O>[CH:1]1([NH:10][CH2:9][CH2:8][NH2:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

5

反応物 2

HCID 3301EthylenediamineHCID 7967Cyclohexanone

生成物 1

HCID 21922N-Cyclohexyl-1,2-ethanediamine

試薬・触媒・溶媒 2

HCID 345198Adams' catalyst触媒HCID 702Ethanol溶媒2 回

実験手順

Cyclohexanone (50 g) and ethylene diamine (60 g) were mixed in ethanol (50 ml) at room temperature and allowed to stand for one hour. Meanwhile Adams catalyst (1 g) in ethanol (20 ml) was pre-reduced on a Parr apparatus at 60 p.s.i. under hydrogen for one hour. The imine solution was added to the hydrogenation flask and reduced at 60 p.s.i. for 18 hours. The catalyst was removed by filtration and the ethanol removed under vacuum. N-Cyclohexyl ethylene diamine was obtained on distillation of the crude product collecting the fraction boiling between 110°-120° C. at 20 ram.

後処理

  1. waitunder hydrogen for one hour
  2. waitfor 18 hours
  3. customThe catalyst was removed by filtration
  4. customthe ethanol removed under vacuum

出典と根拠

ORDレコード
ord-08c1431152a74eacbc3095d247238e08
出典データセット
uspto-grants-1994_08
特許番号
US05338735

反応ノート

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