Methanol → 1,1,2,4,4-Pentamethoxybutane

HRID 1742508

反応式

HRID 1742508 の反応式
C1(C)C=CC(S(O)(=O)=O)=CC=1.CO[CH:14]1[CH:18]=[CH:17][CH:16]([O:19][CH3:20])[O:15]1.[CH3:21][OH:22].[CH:23]([O:28][CH3:29])([O:26][CH3:27])OC>>[CH3:29][O:28][CH:23]([O:26][CH3:27])[CH:18]([O:22][CH3:21])[CH2:17][CH:16]([O:15][CH3:14])[O:19][CH3:20]

参加物

5

反応物 4

HCID 887MethanolHCID 6101p-Toluenesulfonic acidHCID 9005Trimethyl orthoformateHCID 789742,5-Dihydro-2,5-dimethoxyfuran

生成物 1

HCID 187556771,1,2,4,4-Pentamethoxybutane

反応条件

温度
65 °C

実験手順

0.2 g of p-toluenesulfonic acid was added to a solution of 265.3 g (2 mol) of 2,5-dimethoxy-2,5-dihydrofuran (IIa), 384 g (12 mol) of methanol (IIIa) and 214.4 g (2 mol) of trimethyl orthoformate (IVa) in a 2 1 glass reactor, and the mixture was then heated to 65° C. over the course of 20 minutes (min) and finally refluxed for 2 hours (h). The reaction was followed by gas chromatography (percentage areas). The following table shows the course of the reaction to form E,Z-butenedial bis(dimethyl acetal) (Ia) and 1,1,2,4,4-pentamethoxybutane (Va).

後処理

  1. temperaturefinally refluxed for 2 hours (h)
  2. customthe course of the reaction

出典と根拠

ORDレコード
ord-a9b7a4a6a48441558f199af70de591e8
出典データセット
uspto-grants-1994_08
特許番号
US05338888

関連ノート

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