反応式
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=[O:3])[CH3:2].[C:10](OC)(=[O:15])[C:11]([O:13][CH3:14])=[O:12]>>[C:4]1([C:1](=[O:3])[CH2:2][C:10](=[O:15])[C:11]([O:13][CH3:14])=[O:12])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1参加物
3
実験手順
Methyl 4-phenyl-2,4-dioxobutanoate (10 g) obtained by acetophenone and dimethyl oxalate as starting materials and methylhydrazine were reacted in ethanol (60 ml) at a refluxing temperature for 1 h. The solvent was evaporated under reduced pressure, and the obtained residue was purified by silica gel column chromatography (mobile phase:dichloromethane) to give methyl 1-methyl-3-phenylpyrazole-5-carboxylate (3.0 g) and methyl 1-methyl-5-phenylpyrazole-3-carboxylate (3.6 g).
出典と根拠
- ORDレコード
- ord-934e4cba175144f5a2674f8755d35c3d
- 出典データセット
- uspto-grants-2006_03
- 特許番号
- US07015218B1
関連ノート
読み込み中…