Tert-butyl 2-nitro-4-thien-3-ylphenylcarbamate → Tert-butyl [2-amino-4-(3-thienyl)phenyl]carbamate

HRID 1745486

反応式

HRID 1745486 の反応式
[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:18]=[CH:17][S:16][CH:15]=2)=[CH:10][C:9]=1[N+:19]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:18]=[CH:17][S:16][CH:15]=2)=[CH:10][C:9]=1[NH2:19])([CH3:4])([CH3:2])[CH3:3]

参加物

3

反応物 1

HCID 66865115Tert-butyl 2-nitro-4-thien-3-ylphenylcarbamate

生成物 1

HCID 57717476Tert-butyl [2-amino-4-(3-thienyl)phenyl]carbamate

試薬・触媒・溶媒 1

HCID 935Nickel触媒

実験手順

Prepared from (2-nitro-4-thiophen-3-yl-phenyl)-carbamic acid tert.-butyl ester (Example B2) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a white solid (278 mg).

出典と根拠

ORDレコード
ord-b522c29a4c5440afa1f96caff081ea3d
出典データセット
uspto-grants-2006_03
特許番号
US07018998B2

関連ノート

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