Hydrogen Bromide → 6-(2-aminoethyl)pyridin-2(1H)-one hydrobromide
反応式
C[O:2][C:3]1[N:8]=[C:7]([CH2:9][CH2:10][NH2:11])[CH:6]=[CH:5][CH:4]=1.[BrH:12]>>[BrH:12].[NH2:11][CH2:10][CH2:9][C:7]1[NH:8][C:3](=[O:2])[CH:4]=[CH:5][CH:6]=1参加物
3
反応条件
- 温度
- 80 °C
実験手順
To 700 mg of 2-(6-methoxypyridin-2-yl)ethylamine was added 10 ml of a 47% aqueous hydrogen bromide solution, followed by stirring at 80° C. for 60 hours. After evaporating the solvent, the residue was washed with diethyl ether to obtain 1.21 g of a 6-(2-aminoethyl)pyridin-2(1H)-one hydrobromide as a pale brown solid.
後処理
- customAfter evaporating the solvent
- washthe residue was washed with diethyl ether
出典と根拠
- ORDレコード
- ord-a90f43e583a84e3e8228c9acf5d5ea30
- 出典データセット
- uspto-grants-2015_10
- 特許番号
- US09150541B2
反応ノート
読み込み中…