1-(cyclopropylmethyl)-N-methylpiperidine-4-amine → 2-(5-amino-4,6-dimethylpyrimidine-2-yloxy)-N-(1-(cyclopropylmethyl)piperidine-4-yl)-N-methylpropanamide

反応式

C(OC([NH:8][C:9]1[C:10]([CH3:22])=[N:11][C:12]([O:16][CH:17]([CH3:21])[C:18]([OH:20])=O)=[N:13][C:14]=1[CH3:15])=O)(C)(C)C.[CH:23]1([CH2:26][N:27]2[CH2:32][CH2:31][CH:30]([NH:33][CH3:34])[CH2:29][CH2:28]2)[CH2:25][CH2:24]1>>[NH2:8][C:9]1[C:14]([CH3:15])=[N:13][C:12]([O:16][CH:17]([CH3:21])[C:18]([N:33]([CH:30]2[CH2:29][CH2:28][N:27]([CH2:26][CH:23]3[CH2:25][CH2:24]3)[CH2:32][CH2:31]2)[CH3:34])=[O:20])=[N:11][C:10]=1[CH3:22]