1,1-Dichloroethane → (S)-tert-butyl 2-(6-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)dibenzo[b,d]thiophen-3-yl)-1H-benzo[d]imidazol-2-yl)pyrrolidine-1-carboxylate

反応式

CC1(C)C(C)(C)OB([C:9]2[CH:10]=[CH:11][C:12]3[C:16]4[CH:17]=[CH:18][C:19]([B:21]5[O:25][C:24]([CH3:27])([CH3:26])[C:23]([CH3:29])([CH3:28])[O:22]5)=[CH:20][C:15]=4[S:14][C:13]=3[CH:30]=2)O1.Br[C:33]1[CH:34]=[CH:35][C:36]2[N:40]=[C:39]([C@@H:41]3[CH2:45][CH2:44][CH2:43][N:42]3[C:46]([O:48][C:49]([CH3:52])([CH3:51])[CH3:50])=[O:47])[NH:38][C:37]=2[CH:53]=1.C(=O)([O-])[O-].[K+].[K+].ClC(Cl)C>C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.C1(C)C=CC=CC=1.C(COC)OC>[CH3:27][C:24]1([CH3:26])[C:23]([CH3:28])([CH3:29])[O:22][B:21]([C:19]2[CH:18]=[CH:17][C:16]3[C:12]4[CH:11]=[CH:10][C:9]([C:33]5[CH:34]=[CH:35][C:36]6[N:40]=[C:39]([C@@H:41]7[CH2:45][CH2:44][CH2:43][N:42]7[C:46]([O:48][C:49]([CH3:51])([CH3:50])[CH3:52])=[O:47])[NH:38][C:37]=6[CH:53]=5)=[CH:30][C:13]=4[S:14][C:15]=3[CH:20]=2)[O:25]1