N-bromobutanimide → 3-bromo-2-hydroxy-5-methylbenzaldehyde

反応式

[CH3:1][C:2]1[CH:9]=[C:6]([CH:7]=[O:8])[C:5]([OH:10])=[CH:4][CH:3]=1.[Br:11]N1C(=O)CCC1=O>>[Br:11][C:4]1[C:5]([OH:10])=[C:6]([CH:9]=[C:2]([CH3:1])[CH:3]=1)[CH:7]=[O:8]

参加物

反応物 2

HCID 67184N-bromobutanimide

HCID 69184Benzaldehyde, 2-hydroxy-5-methyl-

生成物 1

HCID 27570153-bromo-2-hydroxy-5-methylbenzaldehyde収率 76.1%

実験手順

Proceeding as in Reference 9, but substituting 5-methyl salicylaldehyde (3 g, 22 mmol) and N-bromosuccinimide (4.7 g, 26.4 mmol), gave 3-bromo-2-hydroxy-5-methylbenzaldehyde (3.6 g).

出典と根拠

ORDレコード: ord-bc44c2d3b9df471da839bba48dcb8b3b
出典データセット: uspto-grants-2015_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US09162986B2

反応ノート

読み込み中…