Ethyl bromoacetate → HCID 90093751、化合物
反応式
[CH:1]([C:4]1[NH:8][N:7]=[CH:6][CH:5]=1)([CH3:3])[CH3:2].Br[CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12]>>[CH2:14]([O:13][C:11](=[O:12])[CH2:10][N:8]1[C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][CH:6]=[N:7]1)[CH3:15]参加物
3
実験手順
Prepared according to the method described for Preparation 75 using 5-isopropyl-1H-pyrazole and ethyl bromoacetate. The residue was purified using silica gel column chromatography eluting with 4:1 hexane:EtOAc. The title compound was isolated as the lower running minor product in 6% yield, and taken directly on to the next step.
後処理
- customPrepared
- customThe residue was purified
- washeluting with 4:1 hexane
出典と根拠
- ORDレコード
- ord-d7ba6912db9b4940affd182c946499f4
- 出典データセット
- uspto-grants-2015_10
- 特許番号
- US09163021B2
反応ノート
読み込み中…